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xutianying@smmu.edu.cnPatients with heatstroke often suffer from multiple organ dysfunction and have a high fatality rate.
The molecular mechanisms underlying multiple organ damage in heatstroke are complex.
This review outlines the manifestations of multiple organ dysfunction caused by heatstroke and explores the possible molecular mechanisms involved.
Open Accesshpp510@smmu.edu.cnxutianying@smmu.edu.cnPatients with heatstroke often suffer from multiple organ dysfunction and have a high fatality rate.
The molecular mechanisms underlying multiple organ damage in heatstroke are complex.
This review outlines the manifestations of multiple organ dysfunction caused by heatstroke and explores the possible molecular mechanisms involved.
Heatstroke is a life-threatening acute condition characterized by dysregulated temperature control, resulting in high core temperature and multi-organ dysfunction. Despite extensive research, the molecular mechanisms underlying heatstroke-induced organ damage have not been fully elucidated. This review aims to summarize recent advancements in the field of heatstroke, focusing on etiological factors, organ damage, and molecular mechanisms. By exploring the intricate interplay between heat-related cytotoxicity, inflammatory response, and tissue dysfunction, this review offers insights for future research and clinical practice in managing heatstroke patients. Further investigations are warranted to elucidate the specific mechanisms of organ damage and improve treatment strategies for heatstroke.
ISSN: 2957-5443
Volume 2, Issue 3
September 2024
Pages: 73-123
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