Research Article
Open Access
2024 Sept;2(3):124-132

Construction and comparative analysis of an early screening prediction model for fatty liver in elderly patients based on machine learning

Xiaolei Cai
Xiaolei Cai
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Qi Sun
Qi Sun
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Cen Qiu
Cen Qiu
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Zhenyu Xie
Zhenyu Xie
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Jiahao He
Jiahao He
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Mengting Tu
Mengting Tu
Shanghai DianJi University, Shanghai 201306, China.
,
Xinran Zhang
Xinran Zhang
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Yang Liu
Yang Liu
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Zhaojun Tan
Zhaojun Tan
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Yutong Xie
Yutong Xie
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Xixuan He
Xixuan He
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Yujing Ren
Yujing Ren
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Chunhong Xue
Chunhong Xue
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Siqi Wang
Siqi Wang
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Linrong Yuan
Linrong Yuan
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Miao Yu
Miao Yu
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Xuelin Cheng
Xuelin Cheng
Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.
,
Xiaopan Li
Xiaopan Li
Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.
,
Sunfang Jiang
Sunfang Jiang
jiang.sunfang@zs-hospital.sh.cn
Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.
,
Huirong Zhu
Huirong Zhu
rachel1022@126.com
Tangqiao Community Health Service Center, Shanghai 200127, China.
Address correspondence to
Article notes
Highlights
Sunfang Jiang, Health Management Center, Zhongshan Hospital Affiliated to Fudan University, Gate 5 East Campus, No. 179 Fenglin Road, Xuhui District, Shanghai 200032, China. Email: jiang.sunfang@zs-hospital.sh.cn. Huirong Zhu, Tangqiao Community Health Service Center, No.131 Pujian Road, Pudong New District, Shanghai 200127, China. Email: rachel1022@126.com.
Received May 11, 2024; Accepted July 16, 2024; Published September 30, 2024
  • This study collected three years of physical examination data from older adults in the Tangqiao community of Shanghai, which is more regionally representative.

  • The most suitable model for this study was selected from six machine learning models to construct a fatty liver risk prediction model for the elderly.

  • This study combines six feature selection algorithms with varying performance to screen the features most rele vant to fatty liver.

Research Article
Open Access
Construction and comparative analysis of an early screening prediction model for fatty liver in elderly patients based on machine learning
Xiaolei Cai
Xiaolei Cai
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Qi Sun
Qi Sun
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Cen Qiu
Cen Qiu
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Zhenyu Xie
Zhenyu Xie
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Jiahao He
Jiahao He
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Mengting Tu
Mengting Tu
Shanghai DianJi University, Shanghai 201306, China.
,
Xinran Zhang
Xinran Zhang
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Yang Liu
Yang Liu
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Zhaojun Tan
Zhaojun Tan
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Yutong Xie
Yutong Xie
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Xixuan He
Xixuan He
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Yujing Ren
Yujing Ren
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Chunhong Xue
Chunhong Xue
Tangqiao Community Health Service Center, Shanghai 200127, China.
,
Siqi Wang
Siqi Wang
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Linrong Yuan
Linrong Yuan
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Miao Yu
Miao Yu
Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
,
Xuelin Cheng
Xuelin Cheng
Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.
,
Xiaopan Li
Xiaopan Li
Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.
,
Sunfang Jiang
Sunfang Jiang
jiang.sunfang@zs-hospital.sh.cn
Health Man-agement Center, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China.
,
Huirong Zhu
Huirong Zhu
rachel1022@126.com
Tangqiao Community Health Service Center, Shanghai 200127, China.
Address correspondence to
Sunfang Jiang, Health Management Center, Zhongshan Hospital Affiliated to Fudan University, Gate 5 East Campus, No. 179 Fenglin Road, Xuhui District, Shanghai 200032, China. Email: jiang.sunfang@zs-hospital.sh.cn. Huirong Zhu, Tangqiao Community Health Service Center, No.131 Pujian Road, Pudong New District, Shanghai 200127, China. Email: rachel1022@126.com.
Article notes
Received May 11, 2024; Accepted July 16, 2024; Published September 30, 2024
Highlights
  • This study collected three years of physical examination data from older adults in the Tangqiao community of Shanghai, which is more regionally representative.

  • The most suitable model for this study was selected from six machine learning models to construct a fatty liver risk prediction model for the elderly.

  • This study combines six feature selection algorithms with varying performance to screen the features most rele vant to fatty liver.

2024 Sept;2(3):124-132
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Abstract

Objective: To construct a prediction model for fatty liver disease (FLD) among elderly residents in community using machine learning (ML) algorithms and evaluate its effectiveness. Methods: The physical examination data of 4989 elderly people (aged over 60 years) in a street of Shanghai from 2019 to 2023 were collected. The subjects were divided into a training set and a testing set in a 7:3 ratio. Using feature selection and importance sorting methods, eight indicators were selected, including high-density lipoprotein cholesterol, body mass index, uric acid, triglycerides, albumin, red blood cell, white blood cell, and alanine aminotransferase. Six ML models, including Categorical Features Gradient Boosting, eXtreme Gradient Boosting, Light Gradient Boosting Machine, Random Forest, Decision Tree, and Logistic Regression, were constricted, and their predictive performances were compared via accuracy, precision, recall, F1 score, and Area Under Receiver Operating Characteristic Curve. Results: Among the six ML models, the Categorical Features Gradient Boosting model demonstrated the highest prediction accuracy of 0.74 for FLD in elderly community population, along with a precision of 0.70, a recall of 0.73, a F1 score of 0.71, and an area under the curve of 0.74. Conclusions: In the context of rapid development of artificial intelligence, a community-based elderly FLD prediction model constructed using ML algorithms aid family general practitioners in the early diagnosis, early treatment, and health management of local FLD patients.

Keywords: Fatty liver, machine learning models, disease screening, health management, community diagnosis
Progress in Medical Devices

ISSN: 2957-5478

Volume 2, Issue 3

September 2024

Pages: 89-132

PDF CITE Accesses: 7
Progress in Medical Devices
ISSN: 2957-5478
ZENTIME PUBLISHING CORPORATION LIMITED
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